Innocent vs Organic Murmurs

1. Definition

2. Clinical History

Feature Innocent Murmur Organic Murmur
Symptoms Asymptomatic Dyspnea, feeding difficulty, FTT, syncope
Trigger Fever, anemia, anxiety Often constant; unrelated to high output
Family History Negative May have positive history of CHD or SCD

3. Physical Examination: The "Seven S" Rule

Innocent murmurs typically follow the 7S characteristics:

  1. Sensitive: Changes with position (e.g., louder when supine, softer when standing).
  2. Short: Usually mid-systolic; never holosystolic or diastolic.
  3. Single: No associated clicks or gallops; normal S2 splitting.
  4. Small: Localized area; no wide radiation to back or neck.
  5. Soft: Low intensity (Grade 1-2/6).
  6. Sweet: Musical or vibratory quality (e.g., Still’s murmur).
  7. Systolic: Occurs only during systole (except Venous Hum).

4. Comparison of Auscultatory Features

Parameter Innocent (Physiological) Organic (Pathological)
Intensity Grade ≀ 2/6 Grade β‰₯ 3/6 (with thrill)
Timing Midsystolic (Crescendo-Decrescendo) Pansystolic, Late Systolic, or Diastolic
Quality Musical, vibratory, blowing Harsh, blowing, or "machinery"
S2 Sound Normal physiological splitting Fixed split (ASD) or single S2 (TGA)
Clicks/Snaps Absent Ejection clicks or opening snaps present

5. Red Flags for Organic Murmurs

Presence of any of the following mandates further investigation (ECHO):